Proteins play a fundamental role in biological processes. The genome holds the code for thousands and thousands of proteins that are responsible for maintaining a functioning cellular environment. Protein microarrays are an emerging technology that offers valuable insight into protein development and interaction. This valuable technology has a wide range of applications; from clinical research, to allergy testing a proteome array is an extremely useful tool for understanding the complex proteins that compose your genome.
Protein Microarrays: Applications
Protein microarrays are a valuable tool in clinical research. This advanced technology is being used to understand complex aspects of proteins and the way they function in cellular environments. Using protein microarrays, scientists are able to study the binding characteristics of proteins as well as modifications in their structure that occur after translation. Additionally, these arrays are a great tool for studying and detecting biomarkers in autoimmune diseases. This powerful biological platform is a leading technology in diagnosing protein conditions and studying protein function.
The Different Kinds of Protein Microarrays
Protein microarrays are primarily divided into three categories.
- Analytical protein microarrays. Analytical Protein Microarrays use antibodies to detect proteins in a givens sample. In this form of microarrays, proteins can be detected or labeled in a sample by using a sandwich assay
- Functional protein microarrays. Functional protein microarrays offer the broadest application for studying proteins. Using this microarray technique, scientists are able to gain valuable information about protein binding sites and the enzyme-substrate complex
- Reverse-phase protein microarrays. This method enables scientists to study a multitude of samples at the same time. Through directly applying cell lysates onto a glass slide, scientists are able to study a multitude of proteins.
Protein microarrays are evolving as a powerful platform in proteomic studies. These arrays offer valuable insight into the complex interactions performed by proteins and allow scientists to detect when proteins have been altered after translation.